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叶小芳,吕雪峰.2016.山羊microRNA研究进展.动物学杂志,51(1):137-147.
山羊microRNA研究进展
Advances in goat microRNA
投稿时间:2015-04-14  修订日期:2015-10-27
DOI:DOI: 10.13859/j.cjz.201601016
中文关键词:  microRNA  山羊  基因调控
英文关键词:MicroRNA  Goat  Gene regulation
基金项目:自治区高校科研计划青年教师科研启动基金(XJEDU2011S31);疆师范大学博士科研启动基金(XJNUBS1101);自治区地方公派出国留学成组配套项目(XJDF201327)
作者单位E-mail
叶小芳 新疆师范大学 yxf001982@sina.com 
吕雪峰 新疆畜牧科学院  
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中文摘要:
      小RNA(mcroiRNA,miRNA)是真核生物中发现的一类内源性的具有调控功能的非编码RNA,长度约20-25个核苷酸。研究表明,miRNA参与真核生物的许多生命过程,包括个体发育、新陈代谢、细胞生长和凋亡等方面。目前,关于山羊的miRNA数据相对较少。文章综述了山羊miRNA对皮肤与毛囊发育、肌肉生长发育、泌乳及生殖的调控作用,为利用miRNA调控和改善绒山羊毛绒品质、生长性能及繁殖性能等提供理论基础和研究思路。
英文摘要:
      MicroRNA (miRNA), a class of non-coding RNA (about 20-25 nt), was found in eukaryotes and has function of regulation and control. Many research results have confirmed that miRNAs play an important role in many life processes in eukaryotes, involving the individual development, metabolism, cell growth and apoptosis, etc. At present, there are relatively few miRNA data in goat. This article summarizes the regulation of miRNAs in skin and hair follicle development, muscle growth and development, lactation and reproduction of goat. This review will provide theoretical basis and research insight for using miRNAs to regulate and improve the quality of wool and cashmere, the growth and reproductive performance in goat.
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