• 首页关于本刊期刊订阅编委会作者指南过刊浏览
肖宁,曾祥,周江.2020.贵州省四种蝙蝠携带病毒组.动物学杂志,55(3):339-352.
贵州省四种蝙蝠携带病毒组
Viruses Carried by Four Species of Bats in Guizhou Province
投稿时间:2019-11-12  修订日期:2020-04-30
DOI:10.13859/j.cjz.202003008
中文关键词:  蝙蝠病毒  sRNA  病毒宏基因组学  公共卫生
英文关键词:Bat virus  sRNA  Virus metagenomics  Public health
基金项目:贵州省科技厅自然科学项目(黔科合基础[2016]1004),贵州师范大学地理学一流学科建设项目(黔教科研发[2017]85号),国家重点研发计划项目(No. 2016YFC0503200),国家科技基础条件平台工作重点项目(No. 2005DKA21402)
作者单位E-mail
肖宁 贵阳护理职业学院 贵阳 550000 armiger@163.com 
曾祥 贵州师范大学 贵阳 550000 420495342@qq.com 
周江 贵州师范大学 贵阳 550000 zhoujiang@ioz.ac.cn 
摘要点击次数: 81
全文下载次数: 38
中文摘要:
      翼手目(Chiroptera)动物已被确认是人畜共患病毒的重要自然宿主。贵州省翼手目物种多样性资源丰富,包括了2亚目7科19属65种,但在其携带病毒方面的研究仍然不全面。本文基于病毒宏基因组学和sRNA病毒检测,对贵州省广泛分布的大蹄蝠(Hipposiderideros armiger)、三叶蹄蝠(Aselliscus wheeleri)、贵州菊头蝠(Rhinolophus rex)和皮氏菊头蝠(R. pearsoni)携带的病毒进行注释及鉴定。通过分析得到所携带病毒的种类;并比较了贵州省与云南省和广西省3个地区翼手目携带病毒在种类上的差异。结果显示,在4种蝙蝠中检测出脊椎动物病毒、昆虫病毒、植物病毒、细菌病毒4大类,共计53科111属170余种病毒,其中具有公共卫生学意义病毒9科10属46种,如:人疱疹病毒1型病毒(Human herpesvirus 1)、戊型肝炎病毒(Hepatitis E virus)、人乳头瘤病毒16型(Human papillomavirus type 16)等相关的病毒。贵州省与云南省和广西省3个地区的蝙蝠所携带病毒种类比较发现,只有腺病毒科(Adenoviridae)和逆转录病毒科(Retroviridae)均存在于3个省份的蝙蝠体内,说明病毒种类在不同地域分布的蝙蝠种类中存在较大的差异。贵州省分布的大蹄蝠、三叶蹄蝠、贵州菊头蝠和皮氏菊头蝠携带病毒的种类较多,其病毒种类在公共卫生学上具有一定的代表性,对开展贵州省分子流行病学调查具有重要价值。
英文摘要:
      Chiroptera has been identified as a natural reservoir of emerging infectious diseases for carrying zoonotic viruses. An astonishing amount of genetic diversity of viruses has been isolated from the bats in different populations throughout the world. The diversity resource of chiropteran species in Guizhou province is abundant, consisting 65 species, 19 genera and 7 families of 2 suborders. However, there has been limited research on their zoonotic viruses. In this study, 253 faecal samples and 258 bat tissue samples were collected in Guizhou Province, including 10 species in 2 families, 6 genera (S1). Based on viral metagenomics and sRNA virus detection, this research identified the viruses carried by four species of bats that are widely found in Guizhou Province. By analysing different types of bat viruses, and comparing the species differentiation between bats from Guizhou and those from Yunnan and Guangxi, the study detected four types of viruses in four bat species, including vertebrate viruses, insect viruses, plant viruses and bacterial viruses. Furthermore, there were totally 53 families, 111 genera and more than 170 virus species found, including 9 families, 10 genera and 46 species with public health significance, such as Human herpesvirus 1, Hepatitis E virus, Human papillomavirus type 16 (S2). The comparison of virus species among the three regions revealed that only Adenoviridae and Retroviridae were found in the bats inhabiting in all the three provinces, which might indicate that there could be large differences in types of bat viruses distributed in different regions. Since Chiropterans in Guizhou are found to carry a wide range of virus species which have certain representativeness in public health, it is crucial to carry out further molecular epidemiological investigations.
附件
查看全文  查看/发表评论  下载PDF阅读器