Highly Pathogenic Avian Influenza (HPAI) H5N1 is paid more attention by the human society because it has seriously influenced on the human life,farming,wild birds and ecological environments.It was found currently that AI viruses may affect human and other wild animals by the new subtype or with higher pathogenic through viruses recombination or mutation because people have this H5N1 receptors.AIV surveillance conducted around migratory birds habitats revealed that wetlands,lakes are most possibly the natural origin of AI disease because they may maintain the viruses and spread them through wild bird migration,on the country,these wetlands and their wild birds may therefore face the risk of HPAI.