| 肖调义,刘巧林,章怀云,钟蕾,葛熹凯,许宝红,苏建明.2009.瘟病病毒感染对三角帆蚌主要消化器官的影响.动物学杂志,44(3):1-8. |
| 瘟病病毒感染对三角帆蚌主要消化器官的影响 |
| Effects of Hyriopsis cumingii Plague Virus on Digestive Organs of the H. cumingii |
| 投稿时间：2008-10-31 修订日期：2009-03-16 |
| DOI： |
| 中文关键词: 三角帆蚌 三角帆蚌瘟病病毒 消化腺 消化道 组织病理学 |
| 英文关键词:Hyriopsis cumingii) H.cumingii Plague Virus) Digest gland Enteron Histopathology |
| 基金项目:湖南省科技厅攻关项目(No.06NK3049);湖南省教育厅重点项目(No.07A012) |
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| 中文摘要: |
| 通过人工感染实验,在感染三角帆蚌瘟病病料组织后第3、5、7、9、11d,运用光学显微镜和电子显微镜分别观察了三角帆蚌(Hyriopsis cumingii)主要消化器官的病理变化特征。结果表明,三角帆蚌瘟病病毒(H.cumingiiPlague Virus,HcPV)严重破坏了三角帆蚌消化器官的结构。主要消化腺肝损伤最为严重:光镜下,攻毒7d内腺管肿大,管腔缩小,7d后腺管细胞空泡化并形成多核体;电镜下,线粒体、内质网等细胞器结构破坏,病毒粒子增殖速度快。消化道的病理变化主要表现为胃、肠结构的破坏,胃肠基本结构及感染病毒后的病理变化相似:光镜下,攻毒7d内胃肠结构变化不大,7d后柱状细胞肿大,纤毛脱落,并伴有上皮细胞的脱落;电镜下,细胞器结构破坏,甚至空泡化,病毒粒子前期增殖较慢,后期增殖较快,但总体增殖速度比肝慢。 |
| 英文摘要: |
| The pathological changes of digestive organs were observed by optical microscopy and electron microscopy at the 3rd,5th,7th,9th,and 11th day after artificial infection of Hyriopsis cumingii with the pathological tissue liquid.The results showed that the H.cumingii Plague virus damaged the structure of the digestive organs.The liver was most seriously damaged.This digestive gland was swelling and its lumen was smaller at the 7th day of infection,and after that vacuolation and coenocytes were observed.Under electron microscope,the organelles such as mitochondria and endoplasmic reticulum were damaged and the virus particles were frequently observed.Pathological changes also included stomach and intestine damages.Their structure damage was not obvious within 7 days of infection,but after the 7th day the columnar cells became swellen and the cilia were detached from the epithelial cells.Under electron microscope,organelles damage and even vacuolation were observed.The virus particles became more frequently observed at later stage of infection,but less than observed in the liver. |
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