The concentration of some trace elements, such as zinc(Zn), selenium(Se), copper(Cu), molybdenum(Mo), cobalt(Co), chromium(Cr), manganese(Mn), vanadium(V) and nickel(Ni),in various tissue (e.g. heart, kidney, liver, muscle, lung, stomach and intestine) of three female finless porpoise and three male finless porpoise(Neophocaena asiaeorientalis)in Yangtze River Estuary were measured by inductively coupled plasma mass spectrometer (ICP-MS). The result shows that, many trace elements were detected in various tissue or organs except V. The average content of Zn、Cu and Se were most higher than other elements(59.15±33.87、15.85±15.07 and 7.31±5.49μg/g) , the average content of Cr and Mn were take in second place(3.16±2.70 and 2.35±2.94μg/g) , the average content of Co、Mo、Ni and V were in the last one (0.30±0.48、0.19±0.30、0.12±0.18 and 0.04±0.12μg/g). Overall, the trace elements content in the intestine、liver and kidney of finless porpoise is generally higher than other tissues. The concentration of each elements in some different tissue has a significant difference (p<0.05) except chromium(Cr)(p>0.05). The results also shows that some trace element content in different gender of finless porpoise has a certain difference, like the average content of Mn in male is significantly higher than female(p<0.05) and the average content of Cr in female is significantly higher than male(p<0.01).In addition, these elements are not stable in the same tissues of different individuals of finless porpoise. On average, the variation coefficient of trace elements in different individuals was 121.08%.