Abstract:The crustacean hyperglycemic hormone family,including crustacean hyperglycemic hormone (CHH),molt-inhibiting hormone (MIH),gonad-inhibiting hormone (GIH) and mandibular organ-inhibiting hormone,is found only in crustacean and mostly secreted in the X-organ sinus gland complex of the eyestalk(MOIH).These hormones cooperate to regulate the complicated physiological and biochemical processes,such as growth,reproduction and molt.This review updates the functional properties of CHH family,including the research methods,the functional aspects of each peptide and the regulation of hormone secretion in crustacean.