College of Life Science and Technology,Xinjiang University,Urumqi 830046; Key Laboratory for Cell Differentiation Regulation,Henan Normal University,Xinxiang 453007 在知网中查找 在百度中查找 在本站中查找
Key Laboratory for Cell Differentiation Regulation,Henan Normal University,Xinxiang 453007; College of Life Science,Henan Normal University,Xinxiang 453007,China 在知网中查找 在百度中查找 在本站中查找
Kinetochore is a protein scaffold coordinating the process of chromosome segregation in mitosis. The conserved Ndc80 complex is located on outer kinetochore to connect kinetochore with microtubules,and to stabilize the microtubule-kinetochore attachment. Aurora B /Ipl1 kinase parties involved in correcting the attachment errors. Ndc80 complex is also essential for the functions of spindle assembly checkpoint. This article reviews the current progress in Ndc80 complex studies.
